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KMID : 0375319920140010145
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Journal of Clinical Pathology and Quality Control
1992 Volume.14 No. 1 p.145 ~ p.150
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A Case of pernicious Anemia with Neurologic Dysfunctions
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송원근
어영/신동훈/강명서/심영학
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Abstract
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Pernicious anemia is an etiologic subcategory of megaloblastic anemia caused by a failure of the gastric mucosa to secrete intrinsic factor. In addition to the defective DNA synthesis common to all megaloblastic anemias, there is a defect of
inabilitv
to synthesize myelin that is present only in vitamin B12 deficiency.
We report a case of pernicious anemia associated with neurologic dysfunctions which was diagnosed by bone marrow study, serum level of vitamin B12, and gastrofiberscopy with biopsy.
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KEYWORD
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